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Event Series Event Series: GGA Seminar Series

John Hogenesch, Cincinnati Children’s Hospital Medical Center

February 12 @ 1:30 pm - 2:30 pm

Building circadian medicine in a pediatric hospital

John Hogenesch, Professor of Pediatrics, Division of Human Genetics

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The past several decades has seen an explosion of growth in mechanistic understanding of circadian clocks in several model organisms and in humans. However, translation of that knowledge into actionable medical interventions has been slow to non-existent. Here, I will discuss our efforts to develop circadian medicine in a pediatric hospital. I will talk about our recent progress in understanding the molecular output of the clock in the mouse and humans, including identifying new opportunities for circadian dosing time in improving drug action — hypothesis-driven, mechanistic circadian medicine. I will talk about our efforts to test these hypotheses prospectively in model organisms and retrospectively in large clinical databases. Finally, I will discuss future opportunities and challenges.

Join us on Monday, February 12 at 1:30 PM in Stephens Room (3503 Thomas Hall) and ZOOM for the Genetics and Genomics Seminar Series.

Register to attend virtually via Zoom.

No registration is required to attend In-Person

If you are interested with meeting with John Hogenesch, please contact host Shobhan Gaddameedhi (


February 12
1:30 pm - 2:30 pm
Event Category:




Stephens Room, 3503 Thomas Hall OR Zoom
112 Derieux Place
Raleigh, NC 27607 United States
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