Using gene genealogies to understand complex traits Michael Edge, Assistant Professor of Quantitative and Computational Biology at University of Southern California Twitter | BlueSky Abstract Ancestral recombination graphs (ARGs) use trees to relate variation in a sample of genomes to the genealogical sources of that variation. Recent computational advances have enabled the largest-scale ARG estimates…

Promoting Genetics Awareness with Interdisciplinary and Equitable Approaches Melissa Ramirez, Associate Teaching Professor, Department of Biological Sciences, Director of GGA Undergraduate Programs WPWS | CRECER Abstract This seminar will explore the current goals of the Genetics and Genomics Academy in the context of undergraduate education at NC State. Topics will include courses strategically designed for…

Building circadian medicine in a pediatric hospital John Hogenesch, Professor of Pediatrics, Division of Human Genetics Twitter | Website Abstract The past several decades has seen an explosion of growth in mechanistic understanding of circadian clocks in several model organisms and in humans. However, translation of that knowledge into actionable medical interventions has been slow…

Using DNA sequencing to reveal new insights into human diet Lawrence David, Associate Professor of Molecular Genetics & Microbiology; Associate Director, Duke Microbiome Center Website Abstract Tracking diet by self-reporting often presents challenges, including potential inaccuracies and underreporting. To address these obstacles, we introduce an objective approach for monitoring food species based on DNA sequencing,…

Exploration of cis-regulatory diversity in extant Zea mays Alex Marand, Assistant Professor of Molecular, Cellular, and Developmental Biology at University of Michigan Twitter Abstract Each cell of a multicellular organism generally contains the same DNA sequence. Yet, a single organism is composed of hundreds to thousands of highly diverse and functionally unique cell types. This…